Paraguay competed at the 2011 Pan American Games in Guadalajara, Mexico from October 14 to 30, 2011.

[3] Ben Hockin, a swimmer who won multiple medals at the 2010 South American Games, was selected to carry the flag during the opening ceremonies.

[4] Paraguay qualified one female athlete in artistic roller skating.

[4] Paraguay qualified two athletes in the rowing competition (one male and one female).

Paraguay received one wild card in the women's event.