2K40882015209ENSG00000163666ENSMUSG00000040726Q9UBX0Q61658NM_003865NM_001376058NM_001376059NM_001376060NM_001376061NM_010420NP_003856NP_001362987NP_001362988NP_001362989NP_001362990NP_034550Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene.

[5] Expression of HEX1 and HESX1 marks the anterior visceral endoderm of the embryo.

The AVE is an extra-embryonic tissue, key to the establishment of the anterior-posterior body axis.

Mutations in the HESX1 gene are associated with some cases of septo-optic dysplasia[6] or Pickardt-Fahlbusch syndrome.

This article on a gene on human chromosome 3 is a stub.