The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.

Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem.

The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase.

An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

[7] This article incorporates text from the United States National Library of Medicine, which is in the public domain.