Helper-component proteinase (EC 3.4.22.45, HC-Pro) is an enzyme.
[1][2] This enzyme catalyses the following chemical reaction This enzyme is present in plant RNA viruses of the Potyviridae family.
HC-Pro is encoded by all potyviruses, but is absent in some members of the Ipomovirus genus.
[3] HC-Pro is involved in virus transmission, virus polyprotein processing, and suppression of RNA silencing, an antiviral mechanism of plants.
[4]