Henry Kendall Smith (1811–1854) was Mayor of the City of Buffalo, New York, serving 1850–1851.

Shortly thereafter he moved to Johnstown, New York, to study law, opening a practice in 1832.

In 1833, he moved to Buffalo and began a legal partnership with Israel T. Hatch.

At the outbreak of the Patriot War he was made captain of one of the companies of citizen volunteers.

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