After the death of his first wife, Meigs married widow and poet Mary Noel (née Bleecker) McDonald on November 7, 1848.
[1] On May 16, 1857, an act of the New Jersey Legislature was approved that called for commissioners to be appointed to lay out streets and avenues for the future city of Bayonne.
When Bayonne was incorporated as a city in 1869, Meigs, who was nominated by the citizens' ticket, was elected its first mayor to serve a two-year term on April 13 of that year.
On June 1, 1877, Standard Oil Company opened its first refinery on Constable Hook.
His funeral was held in Trinity Episcopal Church in Bergen Point.