1-Hexadecanethiol is a chemical compound from the group of thiols.

1-Hexadecanethiol is a combustible colorless liquid with an unpleasant odor, which is practically insoluble in water.

The compound is also used for the production of nanoparticles and hydrophobic self-assembling monolayers.

The high affinity of the thiol group to the elements of the copper group causes the thiols to spontaneously deposit in a high-order layer when a corresponding metal of a 1-hexadecanethiol solution is exposed.

[4] The substance decomposes upon combustion with the formation of toxic gases, including sulfur oxides.