The Hillel Yaffe Medical Center (Hebrew: מרכז רפואי הלל יפה) is a major hospital on the western edge of Hadera, Israel.

It serves a population of about 450,000 residents in an area ranging from Zikhron Ya'akov in the north to Netanya in the south, from the Mediterranean coast in the west to Umm el-Fahm and the Green Line in the east.

The center is named after Hillel Yaffe, a pioneering Yishuv doctor who worked in nearby Jewish settlements during the First Aliyah in the early 20th century.

The hospital complex includes the following buildings: A diverse group of doctors and nurses works at the Hillel Yaffe Medical Center: Arabs and Jews, natives and immigrants.

The patients also reflect the diversity of the region's population: urban people alongside rural farmers, natives and immigrants, Jews and Arabs.