Soroka University Medical Center (Hebrew: המרכז הרפואי סורוקה, HaMerkaz HaRefu'i Soroka), a part of the Clalit Health Services Group, is the general hospital of Beersheba, Israel, it serves as the central hospital of the region and provides medical services to approximately one million residents of the South, from Kiryat Gat and Ashkelon to Eilat.

During times of combat in the South (such as Operation Protective Edge and Swords of Iron war), Soroka Medical Center provides service to the injured.

Following the Independence War, the Medical Corps established a temporary military hospital in one of the Ottoman government buildings in Beersheva.

A year later, the hospital was transferred to a British government compound, where it was run by the Hadassah Medical Association and named after Dr. Chaim Yassky.

In 1949, Clalit Health Fund of the Hebrew Workers in Eretz Israel opened a clinic in the city to serve citizens who were members of the Histadrut.

[2] David Tuviyahu, who served as mayor of the city of Beersheva, joined the effort to establish a larger, more spacious and modern hospital.

[3] According to press reports at the time, Dubinsky had indicated that the ILGWU might make a further $500,000 available to the hospital after the $1,000,000 contribution was completed, as the estimated construction cost was $1,500,000.

One of the things that convinced Ben-Gurion was his fear that the planned Sinai War would result in a shortage of hospital beds for wounded soldiers.

[7] In 2004, an Israeli hospital reportedly saved the life of Yahya Sinwar (the future leader of Hamas) by removing a brain tumor from his neck.

Every year, approximately 300 new studies are approved at the hospital, and some 600 articles on research of clinical and managerial significance have been published in the scientific literature.