The Ho Chi Minh City University of Science (HCMUS; Vietnamese: Trường Đại học Khoa học Tự nhiên, Đại học Quốc gia Thành phố Hồ Chí Minh; formerly known as University of Sciences), or VNU-HCM University of Science, offers scientific degrees in Ho Chi Minh City, Vietnam It was established in 1941 as the Indochina College of Science.

[1] VNUHCM-US was re-founded in March 1996 following a split from Đại học Tổng hợp (Ho Chi Minh City University).

In 2007, it was renamed the University of Science, marking a new phase in its role within the VNUHCM system, focusing on public education and research.

As of July 2022, HCMUS has more than 17,000 enrolled students across the following programs: Their joint bachelor programs are in collaboration with: The Honor Program at Vietnam National University, Ho Chi Minh City, aims to cultivate exceptional students in research and advanced technologies.

Students in this program must complete a thesis for graduation.