[2] Holmes has appeared on stage as a stand-up comic and improvisational actress, and has built up a substantial online following.
[3] After limited appearances in short films and television, Holmes landed the co-lead role in the Fox sitcom Welcome to Flatch,[4] which premiered in 2022 and ended in February 2023.
Holmes graduated from Florida State University in 2016 with a Bachelor of Arts degree in English Language and Literature.
[6] Holmes claims no birthplace or hometown in her professional profiles, stating she moved around so much as a child that no one place could be called "home".
She did mention on the Lovett or Leave It podcast episode "The Artful Todger" that her mother lives in Kansas City.