The enzyme homoaconitate hydratase (EC 4.2.1.36) catalyzes the chemical reaction This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds.

The systematic name of this enzyme class is (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming].

Other names in common use include homoaconitase, cis-homoaconitase, HACN, Lys4, LysF, and 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect).

This enzyme participates in lysine biosynthesis.

This EC 4.2 enzyme-related article is a stub.