Horton Run is a 4.36 mi (7.02 km) long tributary to South Branch French Creek in Erie County, Pennsylvania and is classed as a 1st order stream on the EPA waters geoviewer site.

[4] According to the Geographic Names Information System, it has also been known historically as:[1] Horton Run rises in southern Union Township of Erie County, Pennsylvania and then flows northwest to join South Branch French Creek.

Horton Run drains 3.11 square miles (8.1 km2) of Erie Drift Plain (glacial geology).

The watershed receives an average of 46.3 in/year of precipitation and has a wetness index of 468.45.

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