[1] In 1907, the Sisters of Charity of Saint Elizabeth came to New Haven to start the hospital at the request of a group of local physicians, led by Dr. William F.

[2] The doctors asked the Sisters of Charity to administer a hospital that would "receive and care for all patients who might apply for admission without regard to creed or race: To extend charity to the sick, poor, and to offer the institution to those of the medical profession who desire to care for their own patients".

[4] In the 1910s, the Hospital of Saint Raphael received its first X-ray machine, opened its first pharmacy, and acquired its first motorized ambulance.

With a six-story unit facing Chapel Street and five stories on Sherman Avenue, the bed capacity rose to 430.

In the 1970s, a longstanding relationship with Yale School of Medicine was formalized, enhancing St. Raphael's role as a community teaching hospital.

The Verdi Memorial Building opened in 1976, which expanded and improved upon the hospital's surgical, emergency, and intensive care services.

The system grew and became affiliated with Regional Visiting Nurse Agency and Shoreline VNA, both home-care providers.