[2] The hospital provides comprehensive pediatric care to infants, children, teens, and young adults aged 0 to 21[3][4][5] in Connecticut and throughout New England.

Yale New Haven Children's Hospital also features a Level 1 Pediatric Trauma Center, one of two in the state.

[17] In 2018, the hospital opened up a new two-floor neonatal intensive care unit that covers the entire tenth and eleventh floors.

[18][19] The new NICU debuted couplet rooms for mother and baby patients, a feature that is only in one other hospital nationwide.

The hospital also has a 19-bed pediatric intensive care unit to treat critically ill infants, children, teens, and young adults.

[31] In 2018, YNHCH was named to the Parents Magazine list of the "20 most innovative children’s hospitals in the United States.