He graduated from Harvard College with a Bachelor of Science, magna cum laude, in 1926.

[2] Fisher started his career as an architect in 1931 with a solo practice in Chicago, which continued until 1943.

The panels could be assembled in a wide variety of configurations to suit individual clients' needs and specific sites.

The General Houses, Inc. building system was the subject of U.S. patent 1,969,125 issued August 7, 1934.

The first was part of "The Work of the Young Architects of the Midwest" exhibit, which also featured the work of Fisher's rival, Robert W. McLaughlin Jr.[6] Another house, built for Ruth Page was described as an interesting, albeit gloomy, house with an awkward spatial layout.

[2] In 1965 Fisher founded the Harvard Laboratory for Computer Graphics and Spatial Analysis at the Graduate School of Design, serving as its director until 1968.

The prize is co administered by the Center for Geographic Analysis (CGA) and the Harvard Graduate School of Design (GSD), funded by a gift from Jack Dangermond (MLA 1969), President of Environmental Systems Research Institute.