Because cellulose is very crystalline, HPC must have an MS about 4 in order to reach a good solubility in water.

HPC has a combination of hydrophobic and hydrophilic groups, so it has a lower critical solution temperature (LCST) at 45 °C.

[1] Lacrisert, manufactured by Aton Pharma, is a formulation of HPC used for artificial tears.

[6] HPC is used as a thickener, emulsifier, and stabilizer in cosmetic formulations such as shampoos, conditioners, and lotions.

Cellugel is described as "A safe, penetrating consolidant for leather book covers affected by red rot" and is produced by Preservation Solutions.