[citation needed] Hyperplastic polyps on the right side of the colon do exhibit a malignant potential.

[1] The luminal portion has a serrated ("saw tooth") appearance formed by tufts or folds of abundant apical cytoplasm.

[4] They are filled with goblet cells, extending to surface, which commonly has a tufted appearance.

The misplaced epithelium is mucin-depleted, similar to the basal one-third of the polyp.

The misplacement is accompanied by the lamina propria and is continuous with the overlying polyp through a gap in the muscularis mucosae.

[4] The deep proliferative zones and reactive processes closely mimic changes seen in colorectal adenomas.