The IFITM1 gene is located on the Watson (plus) strand of the short arm of chromosome 11 (11p15.5) and is 3,956 bases in length.

[6] In the absence of interferon stimulation, IFITM proteins can express broadly in tissues and cell lines.

IFITM proteins are involved in the physiological process of immune response signaling, germ cell maturation and development.

[11] However, IFITM proteins did not affect alphavirus, arenavirus, or murine leukaemia virus infection.

[13] This article incorporates text from the United States National Library of Medicine, which is in the public domain.