[5] Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes.

It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils.

The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A.

Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.