[5][6][7] This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis.

Reduced expression and rearrangement of this gene have been detected in various cancers.

Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

[7] One of the isoforms of ING1 (p33(ING1) is involved in the modulation of DNA repair.

[9] ING1 is located near the following genes on Chromosome 13 ING1 has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.