The university specializes in career-oriented degree programs in business, engineering, computer science, education, criminal justice, and others.

Beyond its main campus in Fort Wayne, Indiana Tech maintains regional classroom and enrollment centers in 13 locations, including Elkhart, Evansville, Fishers, Greenwood, Huntington, Indianapolis, Jeffersonville, Kendallville, Mishawaka, Munster, and Warsaw in Indiana; and Louisville and Fort Wright in Kentucky.

The American Bar Association (ABA) granted provisional accreditation to Indiana Tech Law School as of March 12, 2016.

In August 2016, Indiana Tech announced the launch of a varsity eSports program that began competition during the fall 2017 academic year.

The program competes in the National Association of Collegiate Esports (NACE), of which Indiana Tech is a founding member.

Indiana Tech also regularly hosts outside performing arts groups and notable speakers from diverse backgrounds in education, business, public service, law and more.

Indiana Tech is also home to a variety of clubs, honor societies, student professional organizations, a local sorority and a national fraternity.