[1] Clarke has built its main campus at Kawagga Close, off Kalungi Road, Muyenga at Block 224 | Plot 8244 Bukasa, Kyadondo, from St. Barnabas Road, Namuwongo a southeastern section of Kampala, Uganda's capital and largest city.

[2] The university has an annex on campus, that is located at St. Agnes Academy, Muwayire Road, Kisugu, Kampala, Uganda, at geographical coordinates: 0°18'21.5"N 32°36'29.5"E (Latitude:0.305972; Longitude:32.608194.

The companies in the group are majority owned by physician, politician, entrepreneur and philanthropist Dr Ian Clarke.

[4] The university incorporated the Uganda Health Management Institute (UHMI), and the International Hospital School of Nursing (IHSON) as the two founding faculties of the university.

[8] As of March 2018[update], the university had one institute and three functional schools:[9] Courses can be pursued (a) full-time (b) part-time (c) on-campus or (d) via remote e-learning.