Intranodal palisaded myofibroblastoma

Intranodal palisaded myofibroblastoma (IPM) is a rare primary tumour of lymph nodes, that classically presents as an inguinal mass.

[citation needed] The main (clinical) differential diagnosis of IPM is metastatic cancer, e.g. squamous cell carcinoma, malignant melanoma, adenocarcinoma.

[citation needed] IPMs are diagnosed by examination of the tissue by a pathologist.

[citation needed] They have a rim of peripheral lymphoid tissue (remnant of a lymph node) and consist of spindle cells with nuclear palisading.

[2] Immunostains for smooth muscle actin and cyclin D1 are characteristically positive.