[1][2][3] Intussusception occurs in normal development as well as in pathologic conditions involving wound healing,[4] tissue regeneration, inflammation as colitis[5][6] or myocarditis,[7] lung fibrosis,[8] and tumors[9][10] amongst others.
Third, a core is formed between the two new vessels at the zone of contact that is filled with pericytes and myofibroblasts.
These cells begin laying collagen fibers into the core to provide an extracellular matrix for growth of the vessel lumen.
During coalescent angiogenesis capillaries fuse and form larger vessels to increase blood flow and circulation.
The degree of intussusceptive angiogenic features in the lungs from the Covid-19 patients were also found to be greater as the length of hospitalization increased (which was not seen in the influenza or control groups).