Vasculogenesis is the process of blood vessel formation, occurring by a de novo production of endothelial cells.
[4] For example, if a monolayer of endothelial cells begins sprouting to form capillaries, angiogenesis is occurring.
Vasculogenesis, in contrast, is when endothelial precursor cells (angioblasts) migrate and differentiate in response to local cues (such as growth factors and extracellular matrices) to form new blood vessels.
Specifically, around blood islands, which first arise in the mesoderm of the yolk sac at 3 weeks of development.
Examples of where vasculogenesis can occur in adults are: This cardiovascular system article is a stub.