Isaak Abramovich Zelensky (Russian: Исаа́к Абра́мович Зеле́нский; 22 June 1890 – 15 March 1938) was a Soviet politician, Communist Party official, and a victim of the Great Purge.

He worked as a party proapagandist in several Russian cities, including Orenburg, Penza, Samara, Tsaritsyn and Moscow,[3] and was arrested several times.

According to the evidence given at his trial in 1938, Zelenksy's brother, Alexander, was exposed in 1924 as a former agent of the Tsarist secret police, the Okhrana, and shot.

In 1929, he was briefly the General Secretary of the Communist Party of Uzbekistan, but in December Akmal Ikramov replaced him as the first ethnic Uzbek in this position.

During the trial, he "confessed" to have been an Okhrana spy, like his brother, since 1911, and that while he was in charge of consumer goods he had arranged to sabotage food distribution by having nails inserted in butter and allowing fifty truckloads of eggs to be spoiled.