Rafiq Nishonovich Nishonov (Cyrillic Uzbek: Рафиқ Нишонович Нишонов; Russian: Рафик Нишанович Нишанов Rafik Nishanovich Nishanov; 15 January 1926[1][2] – 11 January 2023) was the thirteenth First Secretary of the Communist Party of the Uzbek SSR.

In 1950, he worked as the head of the department of the Oktyabrsky district committee of the Komsomol of Uzbekistan in the city of Tashkent.

In 1959, he graduated from the Tashkent Evening Pedagogical Institute with a degree in history teacher.

In 1985, Rafik Nishanov returned to his homeland, where he served as Minister of Foreign Affairs of the Uzbek SSR  .

Like many other leaders in the Uzbek SSR, he strongly opposed allowing Crimean Tatars the right of return and rebuked them for wanting to return to Crimea, even saying that Crimean Tatars who want to leave the Uzbek SSR should find "their place" in faraway Kazan.

His wife Rano Nazarovna was a deputy minister of culture of the Uzbek SSR.