This highly flammable, colorless, and moisture sensitive material is the Grignard reagent derived from isopropyl chloride.
[2] An illustrative reaction involves the generation of the Grignard reagent derived from bromo-3,5-bis(trifluoromethyl)benzene:[3] Addition of one equivalent of LiCl to isopropylmagnesium chloride gives "Turbo Grignard" solutions, named so due to the increased rate and efficiency for transmetalation reactions.
The more reactive species, a LiCl-iPrMgCl complex, is called a Turbo-Grignard reagent.
These species are related to Turbo-Hauser bases, a family of magnesium amido compounds containing also LiCl.
These species promote formation of aryl and heteroaryl Grignard reagents by halogen-magnesium exchange:[9] The traditional method for generating the aryl Grignard reagent proceeds less predictably: Furthermore, traditional routes to Grignard reagents has limited functional group compatibility, whereas the Turbo-Grignard method tolerates other halides, some ester groups, and nitriles.