He was trained at the school of Pierre-Henri de Valenciennes, where he was a student of Jean-Victor Bertin, who influenced him to become a painter of landscapes and historical scenes.
He was, in fact, generally an enthusiast for the Anglomania that developed in France in the 1830s; becoming a member of the circle that surrounded Richard Parkes Bonington, and was one of the first French artists to become interested in the works of John Constable.
His friend, Eugène Delacroix, subsequently became a great admirer of Constable after Regnier presented him with some lithographs from his collection.
This was followed by La Seine et ses abords (1836), Habitations des personnages les plus célèbres de France depuis 1790 jusqu'à nos jours and Promenade dans les rues de Paris, Dessins d’Auguste Regnier, Lithographiés Jean Jacques Champin.
Despite this success with the aristocracy, he fell victim to the increasing fashion for Realism and his career effectively came to an end together with the July Monarchy in 1848.