'place of sandy caves', Nahuatl pronunciation: [ʃaːloːstoːˈtitɬaːn̥]) is a town and municipality located in the northeast corner of the state of Jalisco, Mexico, in a region known as Los Altos.

In 1164, the residents of the area (mostly from the Tecuexe and Caxcan tribes) resisted Aztec advances, who had just settled in nearby Teocaltiche for a period of 40 years before moving on to Tenochtitlán.

Jalostotitlan is the location of sites associated with canonized Mexican Catholic priests Toribio Romo Gonzalez and Pedro Esqueda Ramírez, who were murdered by federal troops during the Cristero War or La Cristiada Jalostotitlán was elevated to city status on 1 September 1970 and made the seat of the municipality.

Jalostotitlán is the birthplace of famed General José María González de Hermosillo, who fought in the Mexican War of Independence.

Most of the residents can trace their ancestry to Spain and France [citation needed] The main activities in the municipality are agriculture, cattle-farming and the services industry.

In the past 15 years Jalostotitlán has become a relevant manufacturing center, producing shoes, leather goods and dairy products.