Jameson Avenue is a multi-lane arterial road in the Parkdale neighbourhood in Toronto, Ontario, Canada.

Jameson Avenue was built in the 1880s as part of the then Village of Parkdale's development, connecting Queen Street to the Lake Ontario waterfront.

As the City of Toronto grew, and with the development of suburbs to the west, east-west automobile traffic in the area increased.

The completion of the Queen Elizabeth Way (QEW) in 1940 meant that Lake Shore Road, and by extension Parkdale, became a major connecting path between downtown Toronto and the highway.

Recently, plans have been made to revamp the area of the demolished neighbourhood, moving the eastbound Lake Shore Boulevard to north of the Gardiner, freeing up space for park uses and enhancing access to the waterfront.