The street passes through several neighbourhoods and landmarks; such as Bloor West Village, Jane and Finch, Vaughan Mills, and Canada's Wonderland.

In Toronto, it primarily passes through residential areas, including the infamous intersection and neighbourhood of Jane and Finch, known for having a high crime rate.

At Teston Road, finally becomes rural and narrows down to two lanes until reaching Davis Drive (formerly Highway 9).

They immigrated from Glasgow in 1907, and a few years later James became a real estate developer in the region north of Toronto (then called York).

[citation needed] Originally, Jane Street continued south to Lake Ontario with a sinuous course, but that section was redesignated as South Kingsway after Bloor Street was linked to its western section in Etobicoke across the Humber River (where it was originally broken) by being realigned into a reverse curve which incorporated a short length of the southern segment of Jane, severing it from the section north of Bloor.

[1] In York Region, YRT route 20 Jane operates from Pioneer Village station to Teston Road.

The 35 Jane would turn at Lambton, and past route 83 Tretheway to run north of Trethewey Drive to Steeles.

However, plans for the LRT have fallen through in recent times, as focus was made to other transit projects, including the Eglinton Crosstown and Finch West LRTs.