Janine van Wyk (born 17 April 1987) is a former South African professional soccer defender, coach, and owner of JVW F.C., a club she founded and bears her name.

[7] A few years later, Van Wyk joined the Moroka Swallows and later, the Palace Super Falcons from Thembisa, where she was part of a team that won three consecutive league titles.

[10] On 1 October 2018 van Wyk was waived by the Houston Dash and placed on re-entry waivers but her rights were not claimed by another team.

[12] After a knee injury during a training session and returning to South Africa, on 14 January 2020, van Wyk announced that she and Fortuna Hjorring had agreed to terminate her contract so she could focus on rehabilitation.

[13] Van Wyk returned to Europe in July 2020 when she signed for Scottish Women's Premier League (SWPL) club Glasgow City.

Van Wyk scored a stunning free kick when Banyana recorded their first ever win over Nigeria since the women's national team was formed in 1993.

[21] Van Wyk played her final match for South Africa on 4 December 2023, helping them secure WAFCON qualification in a 2–0 home victory over Burkina Faso.