The two of them developed a new camera system that allowed Comandon to better isolate syphilis spirochetes based on their characteristic movements.
[2][3] Before and after serving as a physician for the French military during World War I, Comandon worked with Pathé to produce hundreds of educational scientific films on several topics such as microbiology, botany, and infant health.
After Pathé discontinued development of scientific films, Comandon earned a position at the Pasteur Institute with Pierre de Fonbrune, with whom he would go on to found a microcinematography center in Garches.
[5] Although much of Comandon's work was done for commercial purposes, his developments to the practice of microcinematography proved useful in studying bacteria and diagnosing bacterial infections much earlier than previously possible.
The ability to see microbes in motion and, later, the implementation of time-lapse cinematography proved a compelling novelty and made Comandon's films a source of entertainment as well as education.