Tyson earned a bachelor's degree in chemistry from Wheaton College, and received his PhD in chemical physics from the University of Chicago.
By comparing simulations with experimental data, the computer models can be tested, refined and developed, eventually, into tools for accurate predictions of the physiological responses of healthy and diseased cells.
[2] In Tyson's laboratory they study biological systems from a rigorous mathematical perspective, and build realistic models that help gain a deeper understanding of the physiology.
[3] Tyson has published several dynamical models of cell decision making systems in cancer including Estrogen Receptor Signaling, Unfolded Protein Response (UPR) and Autophagy.
Cell Cycle Control by a Minimal Cdk Network was written by Tyson in tandem with Claude Gerard, Damien Coudreuse, and Béla Novák.