Juan Carlos Izpisua Belmonte (born December 12, 1960, in Hellín, Albacete) is a Spanish biochemist and developmental biologist.

He is a professor in the Gene Expression Laboratories at the Salk Institute for Biological Studies in La Jolla, California, US since 1993.

He followed that with a stage as a postdoctoral fellow in different institutions, including the European Molecular Biology Laboratory (EMBL), in Heidelberg, Germany and University of California, Los Angeles (UCLA), Los Angeles, USA prior to moving to the Salk Institute in 1993.

In 2023, due to the interest generated by his work, one of his presentations in Boston drew such a large crowd that it violated the fire code and was reduced by the police.

His work may help to discover new molecules and specific gene/cell treatments to prevent and cure diseases affecting mankind both in the adult and embryonic stages, as well as inducing endogenous in vivo regenerative responses that may allow for tissue and organ regeneration in humans.