The bulk of Upson’s career was devoted to a single series titled The Larry Project – paintings, installations, performances, and films inspired by a collection of one man's personal items she found in 2003.
[11][10] In 2003, after trespassing onto an abandoned property across the street from her parents' home in San Bernardino, Upson discovered boxes of ephemera: letters, legal documents, diaries, photographs, all belonging to one man who she later dubbed 'Larry.
[13] She discovered that 'Larry' styled himself after Hugh Hefner and partied at the Playboy Mansion; he also was involved in a few different self-help programs, including Jungian analysis, chakra cleansing, Gestalt Therapy, and Erhard Seminars Training.
[8] In "Mirrored Staircase Inversion (San Bernardino)" (2011), Upson went back to the site of the original house, which was now an empty dirt lot.
There, she dug into the ground an inverted replica of the twin staircases that had led into 'Larry's' bedroom, and cast the giant hole in latex, creating a skin of the non-existent house.