According to the Italian archaeologist Umberto Scerrato, "the block lies at the eastern base of the little saddle between the two craggy hills below the peak on which the celebrated Cehel Zina of Babur are cut".

[7] In the Kandahar Edict, Ashoka, a patron of Buddhism, advocates the adoption of piety (using the Greek-language term Eusebeia for the Indian concept of Dharma) to the Greek community of Afghanistan.

In the Hellenistic part of the Edict, he translates the Dharma he advocates by "Piety" εὐσέβεια, Eusebeia, in Greek.

The proclamation of this Edict in Kandahar is usually taken as proof that Ashoka had control over that part of Afghanistan, presumably after Seleucos had ceded this territory to Chandragupta Maurya in their 305 BCE peace agreement.

[1][11] At the same epoch, the Greeks were firmly established in the newly created Greco-Bactrian kingdom under the reign of Diodotus I, and particularly in the border city of Ai-Khanoum, not far away in the northern part of Afghanistan.

[4] The Greek and Aramaic versions vary somewhat, and seem to be rather free interpretations of an original text in Prakrit.

[10] It is thought that Old Kandahar was founded in the 4th century BCE by Alexander the Great, who gave it the Ancient Greek name Αλεξάνδρεια Aραχωσίας (Alexandria of Arachosia).

[6][10] The beginning and the end of the fragment are lacking, which suggests the inscription was original significantly longer and may have included all fourteen of Ashoka's Edicts, as in several other locations in India.