Shapandar was a police officer from India who was transformed into an Omega Prime Sentinel by Bastion of the Operation: Zero Tolerance program.

[3] The X-Men discovered a disassembled Karima, along with Lady Mastermind in a lab of the Fordyce Clinic that was testing on mutants to see if someone can catch mutation like a disease.

[6] Omega Sentinel is possessed by Malice, who is now a digital entity instead of a psionic one, via email virus; thus, she unwillingly ends up joining the new Marauders.

The other X-Men, save Emma Frost, were unaware of her being possessed until they were attacked by her along with the rest of the new Marauders, including Mystique and Lady Mastermind.

While Exodus embarks on a personal pilgrimage to this effect, Karima, along with Amelia Voght and Random decide to relocate to San Francisco.

[15] To help deal with the damage to San Francisco done by Bastion and his forces, Cyclops puts together a team of X-Men including Karima.

On the boat trip to the mainland, Karima reveals to Psylocke she has been experiencing some glitches as of late, not knowing that she is actually suffering from the virus unleashed on the Nimrod sentinels during Second Coming.

She decides to sit out for a bit to check on her systems, but her Sentinel technology begins to take over, identifying the threat levels of each of the X-Men present, much to Karima's confusion.

[16] Karima continues battling her fellow X-Men, and when her human side reasserts itself, she asks Hellion to put her out of her misery.

He does so, cutting loose with his telekinetic abilities and causing massive damage to Omega Sentinel, who is left in a coma, possibly brain dead.

[18] A group of X-Men and Sublime hunt her down to the crash site of the meteor in which she arrived on Earth, and confront her in a hospital specializing in mechanical implants.

[19] After being given a complete physical test by Beast, he tells Karima her Omega Sentinel technology has been rendered inert due to Arkea's possession of her and that she is essentially human again.

[21] Somehow, her Sentinel programming was reactivated again and she now travels with members of a new mutant monitoring/profiling organization called Orchis to a new habitat built for humanity.

Headed as the premiere doomsday network prepped in case of the extinction level event pertaining to the population density of Homo Superior; the Orchis Group is backed by numerous clandestine party assets, amongst other black budget and human-centric financial considerations, stemming from A.I.M., S.H.I.E.L.D., Alpha Flight, H.A.M.M.E.R., Hydra, etc.

It wasn't only a mental change she was going through, the once inert physical components of the Omega Sentinel tech had also reactivated, replacing much of her organic tissue in the process.

[22] After Nimrod went online, he challenges Omega Sentinel to share more intel from where she came from, which finally explains what Karima is doing with Orchis.

Karima also claims that she removed Killian Devo's eyes and gave him the artificial ones that he has now which possesses false memories of having been to her future, which is what motivates him to join Orchis.

[23] Karima would spend years as one of Orchis' top lieutenants, notably participating in the massacre and forced exodus of most of mutantkind during the third Hellfire Gala.

When possessed by the biocybernetic enzyme known as Arkea, Karima showcased a number of abilities she'd never readily accessed before such as greater machine and cybernetics control than previously displayed coupled with long range Teleportation capabilities.