It crosses over Ward Branch and curves to a northerly direction, where it begins to parallel Interstate 75 (I-75).

The highway intersects the northern terminus of KY 3429 (Philpot Road) and then crosses over Cloyd and Sampson branches.

On the southwestern edge of London, it intersects KY 1006 (Old Whitley Road) at a roundabout.

It curves to the northeast and intersects the northern terminus of KY 2391 (South Dixie Street).

The highway continues to the northeast and meets its northern terminus, an intersection with U.S. Route 25 (US 25; South Main Street).