Kirkville is a census-designated place and unincorporated community in Itawamba County, Mississippi, United States.

Kirkville is located 0.5 mi (0.80 km) south of the Natchez Trace Parkway.

[4] The Kirkville post office was established prior to the Civil War, and was still in operation in 1905.

[6] The Kirkville Baptist Church and Cemetery are located in the settlement.

This Itawamba County, Mississippi state location article is a stub.