In 1500, the village was acquired by Vilém II of Pernštejn, who already owned large parts of the Pardubice region.

[4] In 1579, Emperor Rudolf II established the Imperial Stud at Kladruby, from which Spanish-blood horses were bred for ceremonial purposes.

On 6 July 2019, the Landscape for Breeding and Training of Ceremonial Carriage Horses at Kladruby nad Labem was inscribed as a UNESCO World Heritage Site.

[8] The site includes the villages of Kladruby nad Labem and Selmice, the Imperial Stud Farm, and the surrounding farmsteads, gardens, pastures, and watercourses.

In addition, the area demonstrates an outstanding example of the ferme ornée style of landscape architecture made popular in the 18th century.