Koula Agagiotou (Greek: Κούλα Αγαγιώτου; 1915 – 25 October 2006) was a Greek actress.
She is probably best known for her role in the Greek sitcom To Retire.
She appeared in more than fifty films, including a well-received performance in the 1971 film Evdokia.
Agagiotou made her film debut in 1951.
She mostly appeared in dramas, and during the 1980s she participated in cult comedies such as Kamikazi Agapi Mou alongside Stathis Psaltis.