[3][4] Krishnam Raju acted in several successful films such as Jeevana Tarangalu (1973), Krishnaveni (1974), Bhakta Kannappa (1976), Amara Deepam (1977), Sati Savitri (1978), Katakatala Rudrayya (1978), Mana Voori Pandavulu (1978), Rangoon Rowdy (1979), Sri Vinayaka Vijayamu (1979), Sita Ramulu (1980), Taxi Driver (1981), Trisulam (1982), Dharmaatmudu (1983), Bobbili Brahmanna (1984), Tandra Paprayudu (1986), Marana Sasanam (1987), Viswanatha Nayakudu (1987), Antima Theerpu (1988), Bava Bavamaridi (1993), Palnati Pourusham (1994).

He joined Bharatiya Janata Party and was elected to the 12th and 13th Lok Sabha from Kakinada and Narasapuram constituencies.

[1] Film producer, Uppalapati Surya Narayana Raju, was his younger brother and actor Prabhas' father.

[10] Krishnam Raju entered Tollywood in 1966 with the film Chilaka Gorinka directed by Kotayya Pratyagatma alongside Krishna Kumari.

[citation needed] Krishnam Raju acted alongside Kanchana in Nenante Nene (1968) and set the trend of handsome villains.

Later he acted in films such as Badi Panthulu (1972), Bala Mitrula Katha (1972), Jeevana Tarangalu (1973), and Kanna Koduku (1973).

Katakataala Rudraiah and Mana Voori Pandavulu was released within a gap of 10 days and both films became blockbusters.

Later he acted in films such as Shivamettina Satyam, Kalyana Chakravarti, and Alludu Pattina Bharatam which were directed by K. Viswanath.

Later he acted in Sita Ramulu, Bebbuli, and Prema Tarangalu, the Telugu remake of the 1978 Bollywood blockbuster Muqaddar Ka Sikandar.

Later he acted in the musical hit, Puli Bidda, Taxi Driver, Ragile Jwala, Guvvala Janta, Rama Lakshmanulu, Madhura Swapnam, Talli Kodukula Anubandham, Nipputo Chelagaatam, Golconda Abbulu, Jaggu, Pralaya Rudrudu, and critically acclaimed Trisulam.

In 1984, Krishnam Raju acted in Yuddham, Sardar, Babulugaadi Debba, Kondaveeti Nagulu and S. P. Bhayankar.

Later, he acted in films such as Raraju, Bharatamlo Shankaravam, Rowdy, Bandee, Tirugubatu, Aggi Raju, Bullet, Ukku Manishi, Ravana Brahma, Neti Yugadharmam, and Ugra Narasimham.

Later, he acted in films such as Sardar Dharmanna and Marana Shasanam which earned him the Filmfare Best Actor Award for the year 1987.

Later, he acted in films such as Maarana Homam, Kirai Dada, Maa Inti Maha Raju, Antima Teerpu, Prithvi Raj, Prachanda Bharatam, Dharma Teja, Prana Snehitulu, Simha Swapnam, Shri Ramachandrudu, Bhagawan, Two Town Rowdy, Yama Dharma Raju and Neti Siddhartha.

In 1991, Krishnam Raju acted in Vidhata, Bava Bavamaridi, Jailor Gaari Abbayi, Andaroo Andare, and Gangmaster.

Later he acted in Chandee, Yevade Subramanyam, and the first Indian 3D historical film, Rudhramadevi where he portrays the role of Ganapati Devudu, father of Rudrama Devi.

The statement of objects and reasons appended to the Bill stated, "Article 48 of the Constitution enjoins on the State to organise agriculture and animal husbandry on modern and scientific lines and in particular to take steps for preserving and improving the breeds and prohibiting the slaughter of cow and its progeny.

In 2000, Krishnam Raju moved a motion in the Lok Sabha for the introduction of The Prohibition of Cow Slaughter Bill, 2000 with the following statement of objects and reasons, "Article 48 of the Constitution enjoins upon the State to organise agriculture and animal husbandry on modern and scientific lines and in particular to take steps for preserving and improving the breeds and prohibiting the slaughter of cow and its progeny.

Setalvad in the Lok Sabha on 1 April 1984 on the issue, to the effect that it was outside the legislative competence of that House to come forward with any Bill concerning the organisation of Agriculture and Animal Husbandry.

However, the Chairman of the Lok Sabha in his ruling on the point raised by Banatwala inter alia observed that the Chair does not decide whether the Bill is constitutionally within the legislative competence of the House or not.

"[16] Raju died on 11 September 2022, at the age of 82, from bacterial and fungal pneumonia followed by cardiac arrest, at the Asian Institute of Gastroenterology Hospitals in Hyderabad, India, which he entered for post-COVID-19 issues on 5 August 2022.