Refugees from Rwanda started to live in Kyangwali when the settlement was opened in the 1960s.

Reportedly, a widespread perception among the more educated refugees is that the agencies promise donors more than they actually deliver.

Although the majority of these refugee-founded agencies rely on their own community resources, and the support of the refugee population itself to help the most vulnerable among them,[5][6] some of the CBOs, such as CIYOTA[7] (the COBURWAS International Youth Organization to Transform Africa[a]), the Planning for Tomorrow Youth Organisation (P4T),[8][9] and Ray of Hope Africa (RAHA),[10] have gone further, and gained national and international recognition from the UNHCR, the World Bank, and other agencies and donors.

Situated just 7 km outside of Kyangwali Refugee Settlement Camp, it serves as a vital healthcare hub where the majority of patients who attend their health days are women, seeking treatment for a range of conditions such as malaria, typhoid, brucellosis, urinary tract infections (UTIs), respiratory infections, pelvic inflammatory disease (PID), pregnancy-related issues, and diarrheal diseases.

[12] In 2021, Reproductive Health Uganda’s (RHU) ACCESS project, funded by the United Kingdom government (UKaid), launched in the Kikuube district to accelerate the acquisition of enhanced and integrated Sexual and Reproductive Health and Rights (SRHR) and family planning services among the refugees and host communities in Kyangwali refugee settlement.