The district headquarters are located at Kikuube, about 25 kilometres (16 mi), southwest of the city of Hoima, the largest urban centre in the Bunyoro sub-region.

[2] Kikuube is located about 215 kilometres (134 mi), by road, northwest of Kampala, Uganda's capital and largest city.

[5] The national population census and household survey held on 27 August 2014 enumerated 267,455 people in the district.

The district population grew at an estimated 5.15 percent average annual rate, between 2014 and 2020.

As of September 2020, in excess of 3,500 smallholder farmers, had signed out-grower contracts with the sugar factory and collectively had over 8,000 hectares (20,000 acres) under sugarcane cultivation.