Ascorbate ferrireductase (transmembrane)

[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction Ascorbate ferrireductase is a diheme cytochrome that acts on hexacyanoferrate(III) and other ferric chelates.

[7] Especially in eukaryotes such as humans, fungi, and bacteria, the upcycle of ascorbate is very important as well as the bioavailability of the ferrous (II) ion.

There are three ways to increase the solubility of Iron (III) and overcome that challenge: chelation, reduction, and acidification.

Reducing the ferric(III) ion to ferrous (II) increases the bio availability which improves the rate and extent at which the aqueous soluble ferrous (II) iron will reach the system of the organism and will prevent the mineralization of the aqueous ferric(III).

[9] Transportation like this mainly takes place in plants and in anaerobic environments where oxidation back to the Iron (III) species is impossible.