She was the daughter of Henry Vane, 1st Earl of Darlington, and his wife, Lady Grace Fitzroy; she was a great-grandchild of Charles II.
[2] In 1746, she married Charles Hope-Vere of Craigiehall and had two sons before the marriage was dissolved by Act of Parliament in 1757, due to the birth of an illegitimate child.
[3] It was claimed by her contemporary J. E. Smith that it was Lady Anne who assisted James Lee in translating Linnaeus's Philosophia Botanica, the first work to explain the Linnaean classification to English readers.
A few years later Lady Anne was introduced to the Danish entomologist Johan Christian Fabricius, one of Linnaeus's pupils.
[1] In 1774, on the way out to Calcutta, Lady Anne visited the Cape of Good Hope where she met another of Linnaeus's pupils, Carl Peter Thunberg, a seasoned collector of South African plants.