Lake Wickenden (French: Lac Wickenden) is the largest lake on Anticosti Island, located in the municipality of L'Île-d'Anticosti, in the Saint Lawrence River, in the Minganie Regional County Municipality, in the region administration of the Côte-Nord, in the province of Quebec, Canada.

A strip of land separates Lac de la Tête and Lake Wickenden.

An access road (coming from the west) serves this hamlet and the south shore of the lake.

The lake was named after Henri Robert Wickenden who worked on Anticosti Island for the Wayagamack Paper Corporation in the 1920s.

[3] The toponym "lac Wickenden" was made official on December 5, 1968 at the Commission de toponymie du Québec place name bank.